Combined screening test


Combined screening test

The combined screening test is a risk free form of prenatal screening to search for an elevated chance of Down-, Edwards- or Pataus syndrome in your baby.

The test consists of two parts:

analysis of the mothers blood– between 9 and 14 weeks of pregnancy

measurement of the nuchal fold of the embryo- between 11 and 14 weeks of pregnancy



For the analysis of the mothers blood a sample will be drawn by the laboratory technician of SHO at Echo Amsterdam. This sample will then be sent to the VU medical centre for analysis of two substances made by the placenta. The concentration of these substances can be different in children with the aforementioned syndromes. The result of this analysis will not be given seperately but will be used to calculate the end result of the test.

Nuchal translucency

Between 11 and 14 weeks an ultrasound scan will be made to measure the nuchal translucency in the embryos neck. This nuchal fold is filled with fluid in every embryo of this age. In children with one of the aforementioned syndromes this layer of fluid is often (much) thicker than in chromosomaly normal children. As far as possible this early in the pregnancy our ultrasound technician will also look for other anomalies of the embryo.


The results of the bloodanalysis and the measurement of the nuchal translucency will be combined with your age and the exact date of your pregnancy in a statistical program. The end result will be an estimate of the chance that your baby has Downs- Edwards- or Pataus syndrome. This test does not give certainty about the syndromes. If your result shows an elevated chance you will be given the choice to do further testing to obtain certainty, like NIPT, Chorionic Villus sampling (CVS) or Amniocentesis (AFT).



Share and Enjoy !

0 0

Beste cliënt,

In verband met het niet kunnen handhaven van de 1,5 meter tijdens het maken van een echo willen wij jullie verzoeken om een mondkapje mee te nemen naar de echo.

Daarnaast mag er naast de zwangere maximaal 1 persoon meekomen naar de echo. Neem dus geen kinderen mee! Wij vragen jullie om niet te vroeg te komen zodat er niet teveel mensen tegelijk in de wachtkamer zitten.

Helaas doen wij op dit moment geen 3D echo's en uitgebreide 2D echo's (pret-echo's).

Bij klachten als hoesten, niezen, koorts en neusverkoudheid vragen wij je om je afspraak telefonisch te verzetten. Een partner met klachten mag niet mee naar binnen.

Alvast bedankt voor jullie medewerking.
met vriendelijke groet,
medewerkers van Echo Amsterdam

Dear cliënt,

Due to the inability to maintain the 1.5 meters range while making an ultrasound, we want to ask you to bring a  facemask to the ultrasound.

You are allowed to bring maximum one extra person besides yourself to your scan. You are not allowed to bring your children.

At this moment do not book in any long scan upon request, that is the 3D scan and the 2D extensive scan.

Please don't arrive too early to prevent too many people in the waiting room at the same time.
When you or your partner are coughing, sneezing or having a fever, we ask you to reschedule your appointment by telephone.

Thanks for your coöperation,
best regards,
the team of Echo Amsterdam